84 capsules - 42 servings
D-aspartic acid is an amino acid that plays a role in increasing luteinizing hormone and testosterone. D-aspartic acid has recently created a huge buzz on the internet. This buzz was brought about by a study showing that at roughly 3gm/day, it can raise testosterone in men by an average of 42%. Now 42% may not sound like much. But considering that an average adult male testosterone level falls between 270-1070ng/dl, a 42% increase would be like going from 500 to almost 900ng/dl!
There have been reported “side-effects” of enhanced frequency and quality of erection. D-aspartic acid exerts its effects partly by increasing cGMP. It’s the increase in cGMP that makes drugs like Viagra and Cialis effective. While not an exact comparison to these drugs, DAA can be marketed as a male enhancement product as well. Effects will not be immediate, but will increase over the first few days.
Testamax is a 21-day supply of DAA that includes DIM to help get rid of any excess estrogen that may result from the natural increase in testosterone. Because of the possibility of increased estrogen and prolactin, we limited the servings to 21, and suggest this as a 3-week cycle product that can be followed up with the Natural PCT or NuTest. Study results showed increased testosterone levels for several days after supplementation ended, so results should not stop suddenly or drop off quickly after use.
Reprod Biol Endocrinol. 2009 Oct 27;7:120.
The role and molecular mechanism of D-aspartic acid in the release and synthesis of LH and testosterone in humans and rats.
Topo E, Soricelli A, D'Aniello A, Ronsini S, D'Aniello G.
1Stazione Zoologica Anton Dohrn, 80121, Villa Comunale, 80121, Napoli, Italy. enza.topo@szn.it
Abstract
BACKGROUND: D-aspartic acid is an amino acid present in neuroendocrine tissues of invertebrates and vertebrates, including rats and humans. Here we investigated the effect of this amino acid on the release of LH and testosterone in the serum of humans and rats. Furthermore, we investigated the role of D-aspartate in the synthesis of LH and testosterone in the pituitary and testes of rats, and the molecular mechanisms by which this amino acid triggers its action.
METHODS: For humans: A group of 23 men were given a daily dose of D-aspartate (DADAVIT) for 12 days, whereas another group of 20 men were given a placebo. For rats: A group of 10 rats drank a solution of either 20 mM D-aspartate or a placebo for 12 days. Then LH and testosterone accumulation was determined in the serum and D-aspartate accumulation in tissues. The effects of D-aspartate on the synthesis of LH and testosterone were gauged on isolated rat pituitary and Leydig cells. Tissues were incubated with D-aspartate, and then the concentration (synthesis) of LH and cGMP in the pituitary and of testosterone and cAMP in the Leydig cells was determined.
RESULTS: In humans and rats, sodium D-aspartate induces an enhancement of LH and testosterone release. In the rat pituitary, sodium D-aspartate increases the release and synthesis of LH through the involvement of cGMP as a second messenger, whereas in rat testis Leydig cells, it increases the synthesis and release of testosterone and cAMP is implicated as second messenger. In the pituitary and in testes D-Asp is synthesized by a D-aspartate racemase which convert L-Asp into D-Asp. The pituitary and testes possesses a high capacity to trapping circulating D-Asp from hexogen or endogen sources.
CONCLUSION: D-aspartic acid is a physiological amino acid occurring principally in the pituitary gland and testes and has a role in the regulation of the release and synthesis of LH and testosterone in humans and rats.
D-aspartic acid is an amino acid that plays a role in increasing luteinizing hormone and testosterone. D-aspartic acid has recently created a huge buzz on the internet. This buzz was brought about by a study showing that at roughly 3gm/day, it can raise testosterone in men by an average of 42%. Now 42% may not sound like much. But considering that an average adult male testosterone level falls between 270-1070ng/dl, a 42% increase would be like going from 500 to almost 900ng/dl!
There have been reported “side-effects” of enhanced frequency and quality of erection. D-aspartic acid exerts its effects partly by increasing cGMP. It’s the increase in cGMP that makes drugs like Viagra and Cialis effective. While not an exact comparison to these drugs, DAA can be marketed as a male enhancement product as well. Effects will not be immediate, but will increase over the first few days.
Testamax is a 21-day supply of DAA that includes DIM to help get rid of any excess estrogen that may result from the natural increase in testosterone. Because of the possibility of increased estrogen and prolactin, we limited the servings to 21, and suggest this as a 3-week cycle product that can be followed up with the Natural PCT or NuTest. Study results showed increased testosterone levels for several days after supplementation ended, so results should not stop suddenly or drop off quickly after use.
Reprod Biol Endocrinol. 2009 Oct 27;7:120.
The role and molecular mechanism of D-aspartic acid in the release and synthesis of LH and testosterone in humans and rats.
Topo E, Soricelli A, D'Aniello A, Ronsini S, D'Aniello G.
1Stazione Zoologica Anton Dohrn, 80121, Villa Comunale, 80121, Napoli, Italy. enza.topo@szn.it
Abstract
BACKGROUND: D-aspartic acid is an amino acid present in neuroendocrine tissues of invertebrates and vertebrates, including rats and humans. Here we investigated the effect of this amino acid on the release of LH and testosterone in the serum of humans and rats. Furthermore, we investigated the role of D-aspartate in the synthesis of LH and testosterone in the pituitary and testes of rats, and the molecular mechanisms by which this amino acid triggers its action.
METHODS: For humans: A group of 23 men were given a daily dose of D-aspartate (DADAVIT) for 12 days, whereas another group of 20 men were given a placebo. For rats: A group of 10 rats drank a solution of either 20 mM D-aspartate or a placebo for 12 days. Then LH and testosterone accumulation was determined in the serum and D-aspartate accumulation in tissues. The effects of D-aspartate on the synthesis of LH and testosterone were gauged on isolated rat pituitary and Leydig cells. Tissues were incubated with D-aspartate, and then the concentration (synthesis) of LH and cGMP in the pituitary and of testosterone and cAMP in the Leydig cells was determined.
RESULTS: In humans and rats, sodium D-aspartate induces an enhancement of LH and testosterone release. In the rat pituitary, sodium D-aspartate increases the release and synthesis of LH through the involvement of cGMP as a second messenger, whereas in rat testis Leydig cells, it increases the synthesis and release of testosterone and cAMP is implicated as second messenger. In the pituitary and in testes D-Asp is synthesized by a D-aspartate racemase which convert L-Asp into D-Asp. The pituitary and testes possesses a high capacity to trapping circulating D-Asp from hexogen or endogen sources.
CONCLUSION: D-aspartic acid is a physiological amino acid occurring principally in the pituitary gland and testes and has a role in the regulation of the release and synthesis of LH and testosterone in humans and rats.
Testamax